Dextromethorphan Hydrobromide 10mg, Chlorpheniramine Maleate 2mg & Phenylephrine Hydrochloride 5mg ( SYRUP ) Manufacturer | Supplier | Franchise

Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL - The syrup is used to treat cold, flu and allergy symptoms. It suppresses coughs, reduces nasal congestion and provides rapid relief from sneezing and runny nose. The multi-action formula of this combination medication offers effective relief in treating dry cough. 

Dextromethorphan is an antitussive(cough suppressant) that is rapidly absorbed and metabolized in the liver. Chlorpheniramine absorbs slowly approx in 2.5 to 6 hours. Phenylephrine first goes into the liver and is destroyed before it can help in your congestion but also has some effect, and is generally safe to use. The syrup is not recommended for children under 12 years. The dosage of this medication depends upon the age, weight and concentration of the syrup formulation.

Medxone Healthcare is an ISO, and WHO-GMP certified company. It manufacturers and supplies dextromethorphan hydrobromide, chlorpheniramine maleate and phenylephrine HCL syrup under the brand name Cricut-DC. The company also offers PCD pharma franchise opportunities and third-party manufacturing services of this syrup.

Mechanism of Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL Syrup

Dextromethorphan Hydrobromide is a cough suppressant that acts centrally on the medulla oblongata to elevate the threshold for coughing. It is a well-known  𝜎-1 receptor agonist which plays a role in cough suppressant. Chlorpheniramine Maleate is a first generation antihistamine that works as a histamine H1 receptor antagonist which reduces allergic reactions such as runny nose, sneezing and watery eyes. Phenylphrine Hydrochloride is a selective 𝛼1-adrenergic receptor agonist that acts as a nasal decongestant. It constricts blood vessels in the nasal mucosa and reduces swelling and congestion. Altogether, these components reduce upper respiratory symptoms by blocking cough reflex and histamines that cause nasal irritation and decreases airway congestion.  

Benefits of Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL Syrup

The following are the key benefits of Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL Syrup.

• Alleviates dry coughs by acting on the cough center in the brain.
• Provides relief from allergy symptoms such as runny nose, sneezing, itching and watery eyes.
• Reduce stuffiness and congestion by narrowing down the blood vessels in the nasal passage 
• Provides a quick and combined effect from cold and cough symptoms.

Side Effects of Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL Syrup

Like every medication, this syrup also has some side effects. Consult your doctor if they persist. Some side effects are as follows.

• Drowsiness 
• Dizziness
• Dry mouth/nose/throat
• Blurred vision
• Constipation
• Nausea
• Headache
• Nervousness
• Increased heart rate
• Restlessness

Precautions of Dextromethorphan Hydrobromide, Chlorpheniramine Maleate and Phenylephrine HCL Syrup

The medication is used for cough and cold and should be taken with appropriate safety measures to avoid potential side effects. When taken as directed, the syrup provides effective relief.

• Consult a doctor in advance if you have glaucoma, urinary problems, an enlarged prostate, thyroid issues, diabetes, heart disease, or high blood pressure.
• Avoid using Monoamine Oxidase Inhibitor in the last 14 days.  
• Do not combine this medication with other antihistamines, psychiatric medications or cold remedies to prevent overdosage.
• Consult with your doctor if symptoms persist for more than 7 days and are accompanied by high fever, rash or headache.
• The syrup is not recommended for pregnant or breastfeeding women.
• It is not suitable for chronic coughs from smoking or asthma.