Glimepiride and Metformin ( TABLETS ) Manufacturer | Supplier | Franchise

Glimepiride and Metformin- The medication is used in the treatment of type 2 diabetes. It belongs to a class of medicines called anti-diabetic drugs. Glimepiride helps pancreas to release more insulin, while Metformin decreases the sugar produced by the liver. This overall helps the body use insulin more effectively.

The tablet works by a dual-action approach that identifies many aspects of type 2 diabetes leading to enhanced glycemic control. Glimpiride binds to specific sulfonylurea receptors(SUR1) on the surface of beta cells.

Glimepiride and Metformin follow strict quality standards to ensure safety and stability. The tablets are easily available in the market to cater patient needs. The medication is manufactured by a reputed company known as Medxone Healthcare. The company uses advanced technology and makes quality products to guarantee purity and reliability. The tablets are recognized as a valuable option in diabetes management.

Mechanism of Glimepiride and Metformin

Metformin works by reducing glucose produced by the liver. It inhibits mitochondrial respiratory chain complex I which affects the cell’s energy balance. It also improves insulin sensitivity particularly in muscle and adipose tissues by increasing glucose utilization. Glimepride stimulates the release of pre-formed insulin from the functional beta cells in the pancreas. It binds to certain sulfonylurea receptors(SUR1) and blocks the ATP-sensitive potassium channels which leads to depolarization of cell membranes. Then an increase in calcium influx occurs when depolarization of the membrane opens voltage-sensitive calcium channels.  

Benefits of Glimepiride and Metformin Tablets

The medication has the following benefits:

• Supports Heart Health: The medication supports cardiovascular health by stabilizing glucose levels and reducing the risk of heart-related diseases.
• Enhanced glucose regulation: The most significant benefit of taking the medication is control over blood glucose levels targeting both fasting and sugar spikes. 
• Affordability: The tablets are a cost-effective option for many patients, especially those who live in resource constraint regions.
• Prevention from Complications: By maintaining blood sugar levels, the tablets help reduce the risk of long-term diabetes-related problems such as kidney damage, vision problems and nerve issues.

Side Effects Of Glimepiride and Metformin Tablets 

Potential Side effects of Glimepiride and Metformin Tablets include:

• Headache
• Dizziness
• Upper Respiratory Tract Infection
• Weight Gain
• Nausea
• Vomiting
• Diarrhoea
• Stomach Pain

Precaution of Glimepiride and Metformin Tablets 

The following are the precautions for Glimepiride and Metformin Tablets:

• The most common side effect of the medication is low blood sugar. Patients consuming these tablets should always carry a fast-acting sugar source like candy or fruit juice.
• Always take a meal on time and do not skip meals.
• Consult with your doctor immediately if you will experience persistent nausea, stomach pain, and unusual tiredness.
• Avoid consuming alcohol as it increases the risk of both lactic acidosis and hypoglycemia.
• Do not consume the tablets if you are pregnant or planning to become pregnant as it can lead to potential risks to the baby’s health.

Storage: 

• Store the tablets in a cool, dry and dark place at room temperature.
• Keep the medicine in an air-tight container to protect it from humidity.
• Keep the medication out of reach of children and pets.