PAFOUT 1GM

Composition : Paracetamol Infusion IP (1.0%W/V)

Packing : 100ML, Bottle With Outer

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Paracetamol Infusion is primarily prescribed to treat and manage mild to moderate pain and the reduction of fever, in cases where oral administration is not possible. It is a sterile, clear solution formulated for intravenous administration. It is a common painkiller used to treat fever and pain.  That works by blocking chemical messengers, such as prostaglandin synthesis, in the central nervous system, responsible for causing pain and fever. Hence, it reduces the pain and fever. Paracetamol Infusions must be administered only under the supervision of a medical professional or a nurse. 

It should not be self-administered. Paracetamol infusion belongs to the drug class known as analgesics, antipyretics. This infusion also exhibits analgesic effects by blocking pain impulse generation without having significant anti-inflammatory properties. Medxone Healthcare is a leading and emerging Pharmaceutical Company, involved in manufacturing and supplying an extensive range of formulations, along with Paracetamol Infusion IP, marketed under the brand name PAFOUT 1GM. Partner with Medxone Healthcare for PCD Pharma Franchise and Third-party manufacturing Business Opportunities. 

What Are The Medical Benefits of Using Paracetamol Infusion?

A List of Medical Benefits of using Paracetamol Infusion has been highlighted as follows:

  • The paracetamol Infusion provides fast-acting analgesia and antipyresis due to direct IV administration as compared to paracetamol Tablets. 
  • This infusion is highly used in post-surgery, in trauma care, or in critical care patients.
  • It acts as a safer alternative compared to certain opioids and NSAIDs.
  • Paracetamol infusion offers quick and effective results in reducing high fever.
  • It is ideal for patients who are unable to take oral medications.
  • It is also effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, menstrual pains, arthritis, and muscle aches.

Mode of Action of Paracetamol Infusion

The working mechanism of Paracetamol Infusion has been discussed in detailed as follows: 

Paracetamol, the active ingredient in the infusion, works by inhibiting the cyclooxygenase (COX-2) enzymes, which are responsible for the production of prostaglandins, the chemical messengers that cause pain and fever. Its antipyretic effect is mediated by acting on the hypothalamic thermoregulatory center, where it lowers body temperature. The analgesic effect works by reducing prostaglandin synthesis in the brain and spinal cord. Hence, resulting in decreased pain. 

What Are The Possible Side Effects of Paracetamol Infusion?

The Paracetamol Infusion may cause some possible side effects. If these side effects persist, immediately consult your doctor or healthcare provider.  A list of Side Effects has been mentioned as follows:

  • Headache
  • Constipation
  • Itching
  • Anxiety
  • Insomnia
  • Nausea
  • Vomiting

General Safety and Precautions

Some Precautions and safety measures have to be followed while using this Paracetamol Infusion. Disclose your previous or recent health issues to your healthcare provider. A list of precautions has been mentioned as follows:

  • If you’re pregnant or breastfeeding, before using this Paracetamol Infusion, consult your doctor or healthcare provider. 
  • This Paracetamol Infusion must be used with caution in individuals suffering from severe kidney problems.
  • Avoid using it if you’ve pre-existing Liver disease. 
  • One should not exceed the recommended daily dosage, as prescribed by the doctor.
  • Use with caution in patients with severe renal impairment or dehydration.
  • This infusion should be administered only by a qualified healthcare professional.

Storage Instructions for Paracetamol Infusion

Follow the instructions mentioned below while storing the Paracetamol Infusion, as follows: 

  • Store the infusion below 25°C. 
  • Protect it from light and avoid freezing. 
  • The solution should be visually checked for particulate matter and discoloration before use. 
  • Do not use if the solution is cloudy or contains particles.

Frequently Asked Questions (FAQ’s)

Q1. How is this infusion administered?

It is administered intravenously (IV) over 15 minutes by a healthcare professional under medical supervision.

Q2. What is the main advantage of using infusion over oral paracetamol tablets?

The infusion works much faster because the medicine goes directly into your bloodstream. It offers rapid and fast relief from pain and fever.

Q3. How long does the effect of a single infusion last?

The pain-relieving effect typically lasts for about 4 to 6 hours.

Q4. Can this be used for severe pain, like after major surgery?

Yes, it is very effective for managing mild to moderate post-operative pain.

Q5. Are there any dietary restrictions while receiving this infusion?

No specific dietary restrictions, but alcohol should be strictly avoided as it increases liver toxicity.

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