Nemusalide 100mg + paracetamol 325mg ( TABLETS ) Manufacturer | Supplier | Franchise

PAFOUT-NP Tablets are a powerful pain-relief formulation combining two highly effective and widely prescribed medicines Nimesulide and Paracetamol. This combination is especially useful in treating mild to moderate pain, inflammation, and fever. It is commonly prescribed for conditions like headache, muscle pain, joint pain, dental pain, postoperative pain, and fever associated with infections.

The blend ensures quicker relief, better pain control, and reduced inflammation while addressing fever simultaneously. PAFOUT-NP is suitable for short-term use and shows a rapid onset of action, making it an effective option for acute pain episodes.

Mechanism of Action

Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the COX-2 enzyme. This leads to a reduction in prostaglandins  the chemicals responsible for pain and inflammation.

Paracetamol (Acetaminophen) works centrally by blocking pain signals in the brain and regulating body temperature via the hypothalamus, making it a potent antipyretic and analgesic.

Together, they provide:

• Faster pain relief
• Reduced inflammation
• Controlled fever
• Improved patient comfort

Indications 

The PAFOUT-NP is prescribed for the treatment of conditions such as:

• Headache & migraine
• Toothache & dental procedures
• Muscle pain & spasms
• Joint pain & arthritis pain
• Fever and flu symptoms
• Postoperative pain
• Ear, nose & throat infections
• Trauma and sports injuries

Dosage & Administration

The PAFOUT-NP Tablets must be taken as prescribed by the doctors, some fo the recommended dosages are : 

• Take PAFOUT-NP Tablet after food to avoid gastric discomfort.
• The usual recommended dose is 1 tablet twice daily, or as directed by your physician.
• Swallow the tablet whole with water.
• Do not crush, chew, or break the tablet.
• Avoid self-medication and do not exceed the prescribed dose.

Side Effects

Most side effects are mild and temporary, including:

• Nausea or vomiting
• Stomach pain or acidity
• Diarrhea
• Drowsiness
• Skin rashes
• Dizziness
• Liver function disturbance
• Gastric bleeding
• Allergic reactions

Precautions

To use the tablet effectively and to prevent unwanted conditions, certain precautions need to be followed, such as : 

• Not recommended for patients with severe liver, kidney, or stomach disorders.
• Avoid alcohol, as it increases liver toxicity risk.
• Not suitable during pregnancy or breastfeeding unless prescribed.
• Caution in patients with heart disease, hypertension, or bleeding disorders.
• Do not take with other painkillers or paracetamol-containing products.
• Avoid prolonged use without a doctor’s supervision.

Storage Instructions

• Store in a cool, dry place below 25°C.
• Keep away from direct sunlight and moisture.
• Keep out of reach of children.
• Do not use if the tablet appears damaged or expired.