Pantoprazole Injection, marketed under the brand name Acihelp-40, is a lyophilized powder for intravenous (IV) use only, with each vial containing 40 mg of Pantoprazole. It is used to reduce stomach acid production and is indicated for conditions like gastroesophageal reflux disease (GERD) and stomach ulcers. Pantoprazole Injection is a proton pump inhibitor (PPI) used to reduce stomach acid production, primarily for treating conditions like gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome.
This injection is commonly used for respiratory, urinary, abdominal, and skin infections, as well as sepsis. It is manufactured and supplied by Medxone Healthcare all over the nation. Their expert team of R&D provides effective and innovative formulations to their patients and tries to meet their unmet needs. They provide ultimate support and guidance to their PCD pharma franchise owners in different locations of India.
Advantages of Pantoprazole Injection
The medical benefits of Pantoprazole injection are as follows:
- Provides fast and effective acid control in emergency situations.
- Suitable for patients who cannot take oral medications due to surgery or illness.
- Highly effective in treating severe gastroesophageal reflux disease (GERD) and peptic ulcers.
- Helps prevent stress-related stomach ulcers in critically ill hospitalized patients.
- Works quicker than oral pantoprazole for rapid symptom relief.
- Lyophilized powder formulation ensures stability and easy reconstitution for IV use.
- Minimal drug interactions compared to other acid-reducing medications.
- Short-term IV therapy reduces the risk of long-term side effects.
- Can be used as an alternative when oral therapy is not feasible.
- Supports faster recovery in acute acid-related digestive disorders.
How to Use Pantoprazole Injection
The usage directions of Pantoprazole injection are given below:
- Administer as an intravenous (IV) infusion only.
- Reconstitute the lyophilized powder with sterile saline before use.
- Do not mix with other medications in the same IV line.
- Infuse over 2-15 minutes as prescribed.
- Use under medical supervision in a clinical setting.
- Store unopened vials at room temperature, protected from light.
- Discard any unused portion after reconstitution.
- Follow the dosage as directed by the healthcare provider.
- Avoid rapid injection to prevent adverse effects.
- Monitor for side effects during and after administration.
How to Store Pantoprazole Injection
The storage instructions for Pantoprazole injection are:
- Store in a cool, dry place away from direct sunlight.
- Keep the injection vials at a temperature not exceeding 25°C.
- Do not freeze the injection solution.
- Protect from moisture and keep the container tightly closed.
- Store in the original packaging until ready for use.
- Keep out of reach of children and pets.
- Check for discoloration or particles before use; discard if present.
- Follow hospital or pharmacy storage guidelines if applicable.
- Do not use if the seal is broken or damaged.
- Discard any unused portion as per medical waste disposal protocols.
Precautions for Pantoprazole Injection
The precautions you should know before the Pantoprazole injection are mentioned below:
- Use with caution in patients with allergies to penicillin or cephalosporins.
- Monitor for signs of hypersensitivity reactions during administration.
- Avoid in patients with severe liver dysfunction or biliary obstruction.
- Assess kidney function before and during therapy.
- The risk of bleeding may increase in patients with vitamin K deficiency.
- Prolonged use may lead to antibiotic-associated diarrhea or colitis.
- Do not mix with alcohol due to disulfiram-like reactions.
- Supervise closely in elderly or debilitated patients.
- Regular blood counts are recommended during extended treatment.
- Use during pregnancy only if needed.
- May cause false-positive urine glucose test results.
- Avoid concurrent use with nephrotoxic or ototoxic drugs.
Side Effects of Pantoprazole Injection
The side effects of using Pantoprazole injection are noted here:
- Headache
- Vomiting
- Joint pain
- Diarrhea
- Dizziness
Frequently Asked Questions (FAQs)
How is Pantoprazole Injection administered?
It is given as a slow intravenous (IV) infusion or injection under medical supervision.
Can it be used during pregnancy?
It should only be used if clearly needed, after consulting a doctor to weigh risks and benefits.
How quickly does it start working?
It begins reducing stomach acid production within 1 hour of administration.
Does it interact with other medications?
It may reduce the absorption of drugs like ketoconazole or iron supplements.
What should I do if a dose is missed?
Administer it as soon as possible, but skip if it’s almost time for the next dose.